Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547684 | 0.84 | PAOX (0.41) | MMP1MMP13ALDH1A1CA1CA2 | |
| SCHEMBL7784845 | 0.83 | TSHR (0.50) | MMP1MMP13ALDH1A1FOLH1MGAM | |
| SCHEMBL16320589 | 0.77 | ALDH1A1 (0.40) | MMP1MMP13ALDH1A1MGAMGAA | |
| SCHEMBL2184012 | 0.77 | ALDH1A1 (0.41) | ALDH1A1FOLH1MGAMGAASI | |
| SCHEMBL2131658 | 0.77 | — | — | |
| SCHEMBL17305959 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL18124773 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL685012 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MGAMGAASIMGAM2 | |
| SCHEMBL20788778 | 0.76 | — | — | |
| SCHEMBL13192691 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5201936-A | Substituted thieno[3,2-b]pyran-5,7-diones | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-13 | — | — | US | disclosed |