⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9648479 | 0.92 | — | — | |
| SCHEMBL1626633 | 0.90 | ALDH1A1 (0.57) | — | |
| SCHEMBL8895897 | 0.90 | ALDH1A1 (0.57) | — | |
| SCHEMBL28219205 | 0.85 | ALDH1A1 (0.62) | — | |
| SCHEMBL218953 | 0.85 | KDM4E (0.60) | — | |
| SCHEMBL49856 | 0.85 | ALDH1A1 (0.62) | — | |
| SCHEMBL9007204 | 0.82 | ALDH1A1 (0.60) | — | |
| SCHEMBL4187314 | 0.82 | KDM4E (0.65) | — | |
| SCHEMBL6636984 | 0.82 | ALDH1A1 (0.67) | — | |
| SCHEMBL466559 | 0.82 | ALDH1A1 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177236-B1 | A METHOD FOR THE FORMATION OF A RAPID-GELLING BIOCOMPATIBLE HYDROGEL AND THE PREPARATION OF A SPRAYING AGENT | BIOREGEN BIOMEDICAL CHANGZHOU (CN) | 2016-11-02 | — | — | EP | claimed |
| US-8647670-B2 | Biocompatible rapid-gelating hydrogel and associated preparation method of spray | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2014-02-11 | — | — | US | claimed |
| US-20100144902-A1 | BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2010-06-10 | — | — | US | claimed |
| EP-2177236-A1 | A METHOD FOR THE FORMATION OF A RAPID-GELLING BIOCOMPATIBLE HYDROGEL AND THE PREPARATION OF A SPRAYING AGENT | Bioregen Biomedical (Changzhou) Co., Ltd. (CN) | 2010-04-21 | — | — | EP | claimed |
| US-11413274-B2 | Methods and compositions associated with the granulocyte colony-stimulating factor receptor | LIGAND PHARMACEUTICALS, INC. (US) | 2022-08-16 | — | — | US | disclosed |
| US-20210046045-A1 | METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2021-02-18 | — | — | US | disclosed |
| US-10736875-B2 | Methods and compositions associated with the granulocyte colony-stimulating factor receptor | LIGAND PHARMACEUTICALS, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-20180369197-A1 | METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2018-12-27 | — | — | US | disclosed |
| US-10111859-B2 | Methods and compositions associated with the granulocyte colony-stimulating factor receptor | LIGAND PHARMACEUTICALS, INC. (US) | 2018-10-30 | — | — | US | disclosed |
| EP-2780322-B1 | METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR | LIGAND PHARM INC (US) | 2018-05-16 | — | — | EP | disclosed |
| US-20160374989-A1 | METHODS AND COMPOSITIONS ASSOCIATED WITH THE GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR | CITIBANK, N.A., AS ADMINISTRATIVE AGENT | 2016-12-29 | — | — | US | disclosed |
| US-9492430-B2 | Methods and compositions associated with the granulocyte colony-stimulating factor receptor | LIGAND PHARMACEUTICALS, INCORPORATED (US) | 2016-11-15 | — | — | US | disclosed |
| EP-1117748-A1 | SEALANT COMPOSITION, ARTICLE AND METHOD | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2001-07-25 | — | — | EP | disclosed |
| WO-2000020526-A1 | SEALANT COMPOSITION, ARTICLE AND METHOD | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |
| US-5580946-A | Thermoplastic polyurethane-epoxy mixtures that develop cross-linking upon melt processing | REFAC INTERNATIONAL, LTD. (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1995013307-A1 | POLYMER VISCOSITY DEPRESSANT/SUPER COOLING THERMOPLASTIC URETHANE | REFAC INTERNATIONAL, LTD. (US) | 1995-05-18 | — | — | WO | disclosed |
| WO-1995013310-A1 | MELT PROCESSED CROSSLINKING THERMOPLASTIC POLYURETHANE-EPOXY MIXTURES | REFAC INTERNATIONAL, LTD. (US) | 1995-05-18 | — | — | WO | disclosed |
| EP-0193346-B1 | PROCESS FOR FORMING A HOT MELT COMPOSITION | GENESCO INC. (US) | 1991-10-23 | — | — | EP | disclosed |
| EP-0193346-A2 | Process for forming a hot melt composition | GENESCO INC. (US) | 1986-09-03 | — | — | EP | disclosed |
| US-4608418-A | POLYURETHANES WITH PLASTICIZERS AND CHAIN EXTENDERS | GENSCO INC. (US) | 1986-08-26 | — | — | US | disclosed |