SCHEMBL959296

SCHEMBL959296

COC(=O)C1=CCC(C)(C(=O)OC)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 2/20 0.39
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
THRB P10828 1/20 0.38
CHRM1 P11229 1/20 0.38
BLM P54132 1/20 0.37
MCOLN3 Q8TDD5 1/20 0.37
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM4E B2RXH2 2/20 0.32
MAPT P10636 2/20 0.32
PTPN1 P18031 1/20 0.31
POLB P06746 2/20 0.31
HSD17B10 Q99714 1/20 0.31
TSHR P16473 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8253101 0.83 CHRM3 (0.37) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL962304 0.75 BRD4 (0.43) LMNAMEN1KMT2AKDM4EMAPT
SCHEMBL13185526 0.72 SRD5A2 (0.35) LMNABLMMEN1KMT2ATSHR
SCHEMBL8254088 0.72 FFAR3 (0.38) CHRM3LMNACHRM2CHRM4CHRM5
SCHEMBL9043652 0.72 SMN1; SMN2 (0.34) MEN1KMT2ASMN1; SMN2
SCHEMBL8187831 0.71 SMN1; SMN2 (0.33) MEN1KMT2ASMN1; SMN2
SCHEMBL21803044 0.69 MEN1 (0.38) LMNAMEN1KMT2AKDM4EMAPT
SCHEMBL29827658 0.68 SMN1; SMN2 (0.35) MEN1KMT2AKDM4EPTPN1SMN1; SMN2
SCHEMBL25905863 0.68 SMN1; SMN2 (0.35) MEN1KMT2AKDM4EPTPN1SMN1; SMN2
SCHEMBL17541038 0.68 ALDH1A1 (0.39) CHRM3LMNACHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617424-B1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME KONICA MINOLTA OPTO INC (JP) 2012-08-15 EP disclosed
US-20110204531-A1 Method of Manufacturing Wafer Lens KONICA MINOLTA OPTO, INC. (JP) 2011-08-25 US disclosed
US-20110111256-A1 Optical Element, Method for Producing Optical Element, and Method for Manufacturing Electronic Device KONICA MINOLTA OPTO, INC. (JP) 2011-05-12 US disclosed
US-20110006447-A1 Method for Producing Hybrid Optical Element Grouping KONICA MINOLTA OPTO, INC. (JP) 2011-01-13 US disclosed
EP-2202739-A1 Diffraction optical device and optical pickup device using the same Konica Minolta Opto, Inc. (JP) 2010-06-30 EP disclosed
US-20080310284-A1 DIFFRACTIVE OPTICAL ELEMENT AND OPTICAL PICKUP APPARATUS KONICA MINOLTA OPTO, INC. (JP) 2008-12-18 US disclosed
EP-1617424-A1 DIFFRACTION OPTICAL DEVICE AND OPTICAL PICKUP DEVICE USING THE SAME Konica Minolta Opto, Inc. (JP) 2006-01-18 EP disclosed