Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9594044 | 0.98 | LMNA (0.58) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL9594194 | 0.94 | LMNA (0.57) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9594034 | 0.93 | LMNA (0.56) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9585385 | 0.85 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL9585390 | 0.85 | LMNA (0.51) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL272391 | 0.82 | LMNA (0.59) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL273324 | 0.82 | LMNA (0.59) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL273323 | 0.82 | LMNA (0.59) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| Ciclactate SCHEMBL2111243 | 0.81 | LMNA (0.62) | LMNANR1I2ABCB11ALDH1A1CYP3A4 | |
| SCHEMBL17639951 | 0.80 | LMNA (0.54) | LMNANR1I2ABCB11ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236946-A | Hypercholesterolemia; regulates cholesterol production by inhibiting HMG-COA reductase | PANMEDICA S.A. (FR) | 1993-08-17 | — | — | US | disclosed |
| US-5134157-A | Trimethylcyclohexyl Pyroglutamate, Antilipemic Agents | PANMEDICA S.A. (FR) | 1992-07-28 | — | — | US | disclosed |