Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19888923 | 0.81 | LMNA (0.59) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL3416759 | 0.81 | KMT2A (0.57) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL662029 | 0.80 | DEGS1 (0.65) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL9595517 | 0.80 | HDAC1 (0.56) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL1193527 | 0.80 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL6292910 | 0.80 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL1193424 | 0.79 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL10185008 | 0.79 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL1193354 | 0.78 | NR1H4 (0.57) | HDAC3HDAC1HDAC2HDAC4HDAC7 | |
| SCHEMBL7866111 | 0.78 | HDAC3 (0.64) | HDAC3HDAC1HDAC2HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227173-B1 | NEW METHOD FOR THE DETECTION OF SPECIFIC BINDING AGENTS AND THEIR CORRESPONDING BINDABLE SUBSTANCES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |
| EP-0227173-A2 | New method for the detection of specific binding agents and their corresponding bindable substances | JANSSEN PHARMACEUTICA N.V. (BE) | 1987-07-01 | — | — | EP | disclosed |