Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD5 | P21918 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9383418 | 1.00 | KDM4E (0.57) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9383413 | 1.00 | KDM4E (0.57) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9377660 | 0.92 | KDM4E (0.50) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL31463068 | 0.92 | KDM4E (0.50) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9376022 | 0.92 | KDM4E (0.50) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL9595435 | 0.92 | KDM4E (0.50) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL8271248 | 0.89 | KDM4E (0.54) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL19852202 | 0.87 | KDM4E (0.55) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL8227830 | 0.86 | ADRA1D (0.59) | KDM4EALOX15TSHRSIRT1KMT2A | |
| SCHEMBL29642368 | 0.83 | KDM4E (0.58) | KDM4EALOX15TSHRSIRT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |