Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595443 | 1.00 | MAPT (0.35) | MAPTKDM4EALDH1A1CYP2C19MEN1 | |
| SCHEMBL9595338 | 0.75 | MAPT (0.40) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL881148 | 0.67 | MAPT (0.46) | MAPTKDM4EALDH1A1CYP2C19L3MBTL1 | |
| SCHEMBL31678235 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL31678395 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL31236855 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL31678384 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL31516170 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL29424301 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 | |
| SCHEMBL29986647 | 0.66 | MAPT (0.44) | MAPTKDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3151363-A | — | — | None | — | — | JP | disclosed |
| US-5225423-A | BUTENONE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES | SHELL RESEARCH LIMITED (GB) | 1993-07-06 | — | — | US | disclosed |
| JP-H03151363-A | BUTENONE COMPOUND, ITS PRODUCTION AND USE AS AGROCHEMICAL | SHELL INTERNATL RES MAATSCHAPPIJ BV | 1991-06-27 | — | — | JP | disclosed |
| EP-0425030-A2 | Butenone compounds, their preparation and their use as pesticides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-05-02 | — | — | EP | disclosed |