SCHEMBL9595338

SCHEMBL9595338

CSC(=CC(=O)C(F)(F)F)SC

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.40
ALDH1A1 P00352 1/20 0.39
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11261334 0.76 MEN1 (0.37) MAPTMEN1KMT2A
SCHEMBL881148 0.76 MAPT (0.46) MAPTALDH1A1KDM4E
SCHEMBL9595448 0.75 MAPT (0.35) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL9595443 0.75 MAPT (0.35) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL31678395 0.74 MAPT (0.44) MAPTALDH1A1KDM4E
SCHEMBL31678235 0.74 MAPT (0.44) MAPTALDH1A1KDM4E
SCHEMBL31516170 0.74 MAPT (0.44) MAPTALDH1A1KDM4E
SCHEMBL31678384 0.74 MAPT (0.44) MAPTALDH1A1KDM4E
SCHEMBL31236855 0.74 MAPT (0.44) MAPTALDH1A1KDM4E
SCHEMBL1492593 0.72 MAPT (0.42) MAPTALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0268915-A2 Trifluoromethylcarbonyl derivatives BAYER AG (DE) 1988-06-01 EP claimed
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2024-12-05 US disclosed
US-11845715-B2 2023-12-19 US disclosed
US-11845715-B2 2023-12-19 US disclosed
US-20220112159-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME UNIV QUEENSLAND (AU) 2022-04-14 US disclosed
EP-3888749-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2021-10-06 EP disclosed
EP-3888749-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2021-10-06 EP disclosed
US-11130731-B2 Sulfonylureas and related compounds and use of same THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2021-09-28 US disclosed
US-11130731-B2 Sulfonylureas and related compounds and use of same THE PROVOST, FELLOWS, FOUNDATION SCHOLARS, AND THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) 2021-09-28 US disclosed
EP-3578547-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME The University of Queensland (AU) 2019-12-11 EP disclosed
US-20150005347-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME MEIJI SEIKA PHARMA CO., LTD. (JP) 2015-01-01 US disclosed
EP-2789237-A1 Pest control agent Meiji Seika Pharma Co., Ltd. (JP) 2014-10-15 EP disclosed
EP-2634174-A2 Nitrogen-containing hetercyclic derivate having 2-imino group and pest control agent including the same Meiji Seika Pharma Co., Ltd. (JP) 2013-09-04 EP disclosed
EP-2631235-A2 Pest control agent Meiji Seika Pharma Co., Ltd. (JP) 2013-08-28 EP disclosed
EP-2628389-A1 NOXIOUS ORGANISM CONTROL AGENT Meiji Seika Pharma Co., Ltd. (JP) 2013-08-21 EP disclosed
US-20130165482-A1 PEST CONTROL AGENT MEIJI SEIKA PHARMA CO., LTD. (JP) 2013-06-27 US disclosed
US-20130150414-A1 PEST CONTROL AGENT MEIJI SEIKA PHARMA CO., LTD. (JP) 2013-06-13 US disclosed
US-5225423-A BUTENONE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES SHELL RESEARCH LIMITED (GB) 1993-07-06 US disclosed
EP-0425030-A2 Butenone compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1991-05-02 EP disclosed
EP-0268915-A2 Trifluoromethylcarbonyl derivatives BAYER AG (DE) 1988-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130150414-A1 PEST CONTROL AGENT PNMT, DDT, ACHE MAPT 2391/4885ALDH1A1 3021/4885MEN1 1282/4885
US-20220112159-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP MAPT 1672/4885ALDH1A1 3558/4885MEN1 3639/4885
US-11845715-B2 NLRP3, PYCARD, NOD1 MAPT 1265/4885ALDH1A1 3407/4885MEN1 4202/4885
US-11130731-B2 Sulfonylureas and related compounds and use of same NLRP3, PYCARD, IAPP MAPT 1672/4885ALDH1A1 3558/4885MEN1 3639/4885
US-20240400502-A1 SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME NLRP3, PYCARD, IAPP MAPT 1672/4885ALDH1A1 3558/4885MEN1 3639/4885
US-20130165482-A1 PEST CONTROL AGENT PNMT, DDT, ACHE MAPT 2391/4885ALDH1A1 3021/4885MEN1 1282/4885
US-20150005347-A1 NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVE HAVING 2-IMINO GROUP AND PEST CONTROL AGENT INCLUDING THE SAME CBR1, CBR3, NIT2 MAPT 4773/4885ALDH1A1 1991/4885MEN1 1211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.