Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.55 |
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | PAM | P19021 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.46 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.46 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9595675 | 1.00 | MMP1 (0.55) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL3324115 | 0.86 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL9762368 | 0.86 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL293067 | 0.86 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL293068 | 0.86 | IDO1 (0.57) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL3295683 | 0.83 | MMP1 (0.54) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL9762373 | 0.83 | MMP1 (0.54) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL113958 | 0.83 | IDO1 (0.58) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL113959 | 0.83 | IDO1 (0.58) | MMP1MMP2MMP9MMP12IDO1 | |
| SCHEMBL12123424 | 0.83 | MMP1 (0.54) | MMP1MMP2MMP9MMP12IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0215739-B1 | SYNTHESIS OF BETA-LACTAM COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |
| EP-0215739-A1 | Synthesis of beta-lactam compounds | CIBA-GEIGY AG (CH) | 1987-03-25 | — | — | EP | disclosed |