Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.80 |
| ▸ | DRD2 | P14416 | 3/20 | 0.80 |
| ▸ | HTR2A | P28223 | 3/20 | 0.80 |
| ▸ | HTR7 | P34969 | 3/20 | 0.80 |
| ▸ | HTR6 | P50406 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | DRD1 | P21728 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9377707 | 0.99 | HTR1A (0.78) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL792775 | 0.90 | HTR1A (0.98) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL2214000 | 0.90 | HTR1A (0.93) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL15064501 | 0.90 | HTR1A (0.85) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9378095 | 0.85 | HTR1A (0.61) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL10518910 | 0.84 | HTR1A (0.72) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9377388 | 0.83 | HTR2A (0.58) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9382112 | 0.81 | HTR1A (0.79) | HTR1ADRD2HTR2AHTR7HTR6 | |
| SCHEMBL9378503 | 0.81 | HTR1A (0.79) | HTR1ADRD2HTR2AHTR7HTR6 | |
| Hydrochloric Acid SCHEMBL9604507 | 0.81 | HTR1A (0.79) | HTR1ADRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016073-A1 | PIPERAZINE AND PIPERIDINE DERIVATIVES, AND THEIR USE AS ANTIPSYCHOTICS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-08-19 | — | — | WO | disclosed |