Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | ECE1 | P42892 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30210348 | 0.87 | LMNA (0.49) | LMNAPOLBSMN1; SMN2GBA2DPP4 | |
| SCHEMBL6420027 | 0.86 | LMNA (0.46) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL30816157 | 0.84 | LMNA (0.54) | LMNAPOLBSMN1; SMN2GBA2DPP4 | |
| SCHEMBL27151384 | 0.84 | LMNA (0.54) | LMNAPOLBSMN1; SMN2GBA2DPP4 | |
| SCHEMBL9596636 | 0.84 | LMNA (0.43) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL9597320 | 0.83 | LMNA (0.43) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL1542778 | 0.79 | LMNA (0.49) | LMNAPOLBSMN1; SMN2GBA2DPP4 | |
| SCHEMBL3333110 | 0.78 | LMNA (0.54) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL9597059 | 0.77 | NR1H2 (0.47) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL15391908 | 0.77 | LMNA (0.48) | LMNAPOLBSMN1; SMN2GBA2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993018016-A1 | FUNGICIDAL OXAZOLIDINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-16 | — | — | WO | disclosed |
| WO-1993003026-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1993-02-18 | — | — | WO | disclosed |