SCHEMBL9596381

SCHEMBL9596381

C#CC(C)(C)c1c(Cl)ccc([O])c1Cl

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
MAPK1 P28482 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9594463 0.78 NOTUM (0.33) MEN1MAPK1KMT2A
SCHEMBL9594167 0.70
SCHEMBL9130682 0.67
SCHEMBL16307979 0.65 NOTUM (0.37) MEN1KMT2A
SCHEMBL27703271 0.63 KCNN4 (0.43) MEN1MAPK1KMT2A
SCHEMBL302009 0.62 CYP3A4 (0.46) MEN1MAPK1KMT2A
SCHEMBL5961683 0.62 CES1 (0.36)
SCHEMBL9593594 0.61 ALDH1A1 (0.33)
SCHEMBL3105850 0.61 MEN1 (0.37) MEN1MAPK1KMT2A
SCHEMBL9889139 0.59 NOTUM (0.38) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5203907-A Herbicides BASF AKTIENGESELLSCHAFT (DE) 1993-04-20 US disclosed