Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | BRD4 | O60885 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.55 |
| ▸ | BRD2 | P25440 | 1/20 | 0.54 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.54 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | VEGFA | P15692 | 2/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597407 | 1.00 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL9359822 | 0.99 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL9356197 | 0.99 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL9356502 | 0.92 | BRD4 (0.60) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL9596710 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL9596784 | 0.90 | ALDH1A1 (0.64) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL9356509 | 0.89 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| Hydrochloric Acid SCHEMBL9356571 | 0.89 | ALDH1A1 (0.63) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL9596601 | 0.89 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ABRD4 | |
| SCHEMBL9603241 | 0.89 | ALDH1A1 (0.65) | ALDH1A1MAPTMEN1KMT2ABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015056-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | claimed |
| WO-1993015056-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |