Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18498621 | 0.86 | LMNA (0.56) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL9596873 | 0.83 | LMNA (0.44) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL9596636 | 0.82 | LMNA (0.43) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL6420027 | 0.81 | LMNA (0.46) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL1633241 | 0.79 | LMNA (0.56) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL1542778 | 0.79 | LMNA (0.49) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL14034308 | 0.78 | LMNA (0.48) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL14034326 | 0.78 | LMNA (0.48) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL20605787 | 0.77 | SMN1; SMN2 (0.47) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 | |
| SCHEMBL20912047 | 0.76 | POLB (0.56) | LMNAPOLBSMN1; SMN2GBA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993003026-A1 | NOVEL QUINOLONE CARBOXYLIC ACID DERIVATIVES | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 1993-02-18 | — | — | WO | disclosed |