Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | BRD2 | P25440 | 1/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.53 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597519 | 1.00 | BRD4 (0.54) | BRD4BRD2BRD3BRDTNPC1 | |
| Hydrochloric Acid SCHEMBL9356749 | 0.99 | BRD4 (0.53) | BRD4BRD2BRD3BRDTNPC1 | |
| Hydrochloric Acid SCHEMBL9356578 | 0.99 | BRD4 (0.53) | BRD4BRD2BRD3BRDTNPC1 | |
| Hydrochloric Acid SCHEMBL9356502 | 0.88 | BRD4 (0.60) | BRD4BRD2BRD3BRDTRAB9A | |
| SCHEMBL9596491 | 0.88 | BRD4 (0.50) | BRD4BRD2BRD3BRDTRAB9A | |
| SCHEMBL9596601 | 0.87 | ALDH1A1 (0.65) | BRD4BRD2BRD3BRDTRAB9A | |
| SCHEMBL9603241 | 0.87 | ALDH1A1 (0.65) | BRD4BRD2BRD3BRDTRAB9A | |
| Hydrochloric Acid SCHEMBL9356172 | 0.87 | BRD4 (0.49) | BRD4BRD2BRD3BRDTRAB9A | |
| Hydrochloric Acid SCHEMBL9356549 | 0.86 | MAPT (0.53) | BRD4BRD2BRD3BRDTNPC1 | |
| Hydrochloric Acid SCHEMBL9356547 | 0.86 | ALDH1A1 (0.64) | BRD4BRD2BRD3BRDTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993015056-A1 | PYRIDONE DERIVATIVES, THEIR PREPARATION AND USE AS MEDICINES | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1993-08-05 | — | — | WO | disclosed |