Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.56 |
| ▸ | FNTA | P49354 | 7/20 | 0.55 |
| ▸ | FNTB | P49356 | 7/20 | 0.55 |
| ▸ | PGGT1B | P53609 | 7/20 | 0.55 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597700 | 1.00 | LTA4H (0.56) | LTA4HNAALAD2FNTAFNTBPGGT1B | |
| SCHEMBL29630499 | 0.97 | NAALAD2 (0.57) | LTA4HNAALAD2FNTAFNTBPGGT1B | |
| SCHEMBL29489259 | 0.94 | LTA4H (0.60) | LTA4HNAALAD2FNTAFNTBPGGT1B | |
| SCHEMBL6241495 | 0.92 | LTA4H (0.60) | LTA4HNAALAD2FNTAFNTBPGGT1B | |
| SCHEMBL8644611 | 0.92 | FNTA (0.62) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL8644625 | 0.92 | FNTA (0.62) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL29630374 | 0.92 | BACE1 (0.62) | BACE1 | |
| SCHEMBL29378966 | 0.91 | FNTA (0.58) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL30050929 | 0.90 | FNTA (0.59) | LTA4HFNTAFNTBPGGT1B | |
| SCHEMBL29591515 | 0.90 | BACE1 (0.57) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0218651-B1 | A DNA SEQUENCE | NOVO NORDISK A/S (DK) | 1993-08-11 | — | — | EP | disclosed |
| EP-0218651-A1 | A DNA SEQUENCE. | NORDISK GENTOFTE (DK) | 1987-04-22 | — | — | EP | disclosed |
| WO-1986005804-A1 | A DNA SEQUENCE | NORDISK GENTOFTE A/S (DK) | 1986-10-09 | — | — | WO | disclosed |