Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 6/20 | 0.54 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | CLK2 | P49760 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9293080 | 0.97 | TOP2A (0.56) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL9598155 | 0.92 | TOP2A (0.44) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8136415 | 0.91 | ALDH1A1 (0.56) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL9293538 | 0.90 | ALDH1A1 (0.53) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8137471 | 0.87 | ALDH1A1 (0.52) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8137466 | 0.87 | ALDH1A1 (0.52) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8137477 | 0.87 | ALDH1A1 (0.52) | TOP2ATOP2BALDH1A1POLBOPRM1 | |
| SCHEMBL8133566 | 0.82 | KCNH2 (0.68) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL8134406 | 0.82 | KCNH2 (0.68) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9670575 | 0.82 | KCNH2 (0.60) | TOP2ATOP2BALDH1A1POLBOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993024481-A1 | 7-SUBSTITUTED-6-FLUORO-1,4-DIHYDRO-4-OXO-QUINOLINE-3-CARBOXYLIC ACID COMPOUNDS AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | SYNPHAR LABORATORIES, INC. (CA) | 1993-12-09 | — | — | WO | disclosed |