⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15747902 | 0.92 | SLC6A4 (0.30) | — | |
| SCHEMBL15750146 | 0.88 | SLC6A4 (0.33) | — | |
| SCHEMBL15750155 | 0.85 | — | — | |
| SCHEMBL15750147 | 0.85 | — | — | |
| SCHEMBL15748128 | 0.84 | MMP2 (0.31) | — | |
| SCHEMBL15748038 | 0.84 | — | — | |
| SCHEMBL17192589 | 0.81 | EPHX2 (0.30) | — | |
| SCHEMBL15750317 | 0.81 | SLC6A4 (0.33) | — | |
| SCHEMBL17304953 | 0.80 | PIM1 (0.30) | — | |
| SCHEMBL17304959 | 0.80 | PIM1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5241069-A | Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives | GLAXO INC. (US) | 1993-08-31 | — | — | US | disclosed |
| EP-0489876-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1991015447-A1 | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-17 | — | — | WO | disclosed |
| US-5057630-A | SYNTHESIS OF CYCLOPENTENE DERIVATIVES | GLAXO INC. (US) | 1991-10-15 | — | — | US | disclosed |