Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.51 |
| ▸ | CNR1 | P21554 | 5/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9249796 | 0.86 | MAPT (0.50) | TLR4TLR2RAB9AMAOBMAOA | |
| SCHEMBL6841844 | 0.80 | MAPT (0.55) | CNR2CNR1CYP19A1RAB9AMAOB | |
| SCHEMBL6836524 | 0.78 | MAPT (0.58) | CNR2CNR1CYP19A1TLR4TLR2 | |
| SCHEMBL6841271 | 0.78 | MAPT (0.53) | CNR2CNR1CYP19A1MAOBMAOA | |
| SCHEMBL6942590 | 0.77 | MAPT (0.46) | CNR2CNR1CYP19A1TLR4TLR2 | |
| SCHEMBL4847069 | 0.74 | F2 (0.55) | TLR4TLR2RAB9A | |
| SCHEMBL8986112 | 0.74 | MAOB (0.62) | TLR4TLR2MAOBMAOAMEN1 | |
| SCHEMBL13904132 | 0.74 | APP (0.66) | RAB9A | |
| SCHEMBL9597967 | 0.73 | RAB9A (0.46) | RAB9AMAOBMAPT | |
| SCHEMBL18429630 | 0.72 | APP (0.59) | RAB9AMAOBMAOAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5196422-A | Antiinflammatory agents, antiallergens | ICI PHARMA (FR) | 1993-03-23 | — | — | US | disclosed |
| US-5089513-A | Antiinflammatory agents; antiallergens; asthma; side effect reduction | ICI PHARMA (FR) | 1992-02-18 | — | — | US | disclosed |