⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29928488 | 0.86 | TAAR1 (0.37) | — | |
| SCHEMBL25772209 | 0.80 | PIK3CD (0.32) | — | |
| SCHEMBL25799051 | 0.80 | PIK3CD (0.32) | — | |
| SCHEMBL13655453 | 0.80 | PIK3CD (0.32) | — | |
| SCHEMBL11231368 | 0.79 | PIK3CD (0.39) | — | |
| SCHEMBL12663186 | 0.77 | SIGMAR1 (0.34) | — | |
| SCHEMBL11131387 | 0.76 | PLA2G1B (0.32) | — | |
| SCHEMBL23958404 | 0.75 | CA12 (0.46) | — | |
| SCHEMBL17238884 | 0.75 | — | — | |
| SCHEMBL22759379 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219480-A | ETHYLENE ALPHA-OLEFIN MANNICH BASE VISCOSITY INDEX IMPROVER/DISPERSANT ADDITIVES DERIVED FROM AMINO PHENOLS AND MONOSECONDARY AMINES | EXXON CHEMICAL PATENTS INC. (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0357215-A1 | Ethylene alpha-olefin mannich base viscosity index improver/dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-03-07 | — | — | EP | disclosed |