Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.36 |
| ▸ | QPCT | Q16769 | 3/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IRS1 | P35568 | 1/20 | 0.35 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844235 | 1.00 | KDM4E (0.48) | KDM4ERAB9AHTR2ADRD2SLC6A2 | |
| SCHEMBL9597616 | 0.93 | KDM4E (0.48) | KDM4ERAB9AHTR2ADRD2SLC6A2 | |
| SCHEMBL9597598 | 0.93 | KDM4E (0.48) | KDM4ERAB9AHTR2ADRD2SLC6A2 | |
| SCHEMBL15164266 | 0.82 | KDM4E (0.68) | KDM4ERAB9AHTR2ASLC6A2HTR2C | |
| SCHEMBL9598576 | 0.81 | RAB9A (0.48) | KDM4ERAB9AALDH1A1GPR3RARB | |
| SCHEMBL9597624 | 0.81 | RAB9A (0.48) | KDM4ERAB9AALDH1A1GPR3RARB | |
| SCHEMBL9702885 | 0.81 | KDM4E (0.66) | KDM4ERAB9AHTR2ASLC6A2HTR2C | |
| SCHEMBL10058957 | 0.81 | RAB9A (0.59) | KDM4ERAB9AALDH1A1AKT1MEN1 | |
| SCHEMBL10058949 | 0.81 | RAB9A (0.59) | KDM4ERAB9AALDH1A1AKT1MEN1 | |
| SCHEMBL10058950 | 0.81 | RAB9A (0.59) | KDM4ERAB9AALDH1A1AKT1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5213709-A | Contains thiadiazole ring | CANON KABUSHIKI KAISHA (JP) | 1993-05-25 | — | — | US | disclosed |
| EP-0455219-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1991-11-06 | — | — | EP | disclosed |