Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11587163 | 0.90 | GRIK1 (0.41) | GRIK1GRIK2CTSKCHRM1 | |
| SCHEMBL11586875 | 0.77 | CTSK (0.35) | GRIK1GRIK2CTSK | |
| SCHEMBL14214372 | 0.73 | — | — | |
| SCHEMBL15549648 | 0.73 | — | — | |
| SCHEMBL4289130 | 0.73 | — | — | |
| SCHEMBL18969754 | 0.73 | — | — | |
| SCHEMBL446242 | 0.73 | SLC1A2 (0.32) | — | |
| SCHEMBL576851 | 0.73 | — | — | |
| SCHEMBL12230325 | 0.73 | — | — | |
| SCHEMBL25575102 | 0.73 | GRIK1 (0.42) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013104-A1 | C.N.S. ACTIVE TRICYCLIC THIENOPYRIDINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 1993-07-08 | — | — | WO | disclosed |