Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.58 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.58 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.58 |
| ▸ | ALB | P02768 | 1/20 | 0.58 |
| ▸ | PGR | P06401 | 2/20 | 0.58 |
| ▸ | APAF1 | O14727 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | SNCA | P37840 | 1/20 | 0.57 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.57 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | ABCC4 | O15439 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 8/20 | 0.56 |
| ▸ | APEX1 | P27695 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9600120 | 1.00 | NR1I2 (0.60) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9623352 | 0.91 | NR1I2 (0.73) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9623349 | 0.91 | NR1I2 (0.73) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9623446 | 0.91 | NR1I2 (0.73) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9623443 | 0.91 | NR1I2 (0.73) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9623411 | 0.89 | APAF1 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9624145 | 0.89 | APAF1 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9623415 | 0.89 | APAF1 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9624148 | 0.89 | APAF1 (0.63) | NR1I2HTR2CMAPTPPARGSLC22A6 | |
| SCHEMBL9601567 | 0.87 | KMT2A (0.46) | NR1I2HTR2CMAPTPPARGSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| EP-0188254-A2 | Cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |