Hydrochloric Acid

Hydrochloric Acid

SCHEMBL960034

CCCCCn1cc[n+](CCC)c1.[Cl-]

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
HSP90AA1 P07900 2/20 0.58
KMT2A Q03164 2/20 0.58
SMN1; SMN2 Q16637 2/20 0.58
APAF1 O14727 1/20 0.56
NPC1 O15118 1/20 0.56
PLA2G1B P04054 1/20 0.56
MAPT P10636 1/20 0.56
MAPK1 P28482 1/20 0.56
HTT P42858 1/20 0.56
RAB9A P51151 1/20 0.56
NPSR1 Q6W5P4 1/20 0.56
ATG4B Q9Y4P1 1/20 0.56
FDPS P14324 17/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11538572 0.98 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
Hydrochloric Acid SCHEMBL958505 0.98 MEN1 (0.60) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL961669 0.98 MEN1 (0.59) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL5291994 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL5290107 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL5288264 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL5301127 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL5288678 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL4266804 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1
SCHEMBL5289982 0.96 MEN1 (0.62) MEN1HSP90AA1KMT2ASMN1; SMN2APAF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9267214-B2 Aluminum recovery process BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-02-23 US claimed
US-20110000782-A1 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2011-01-06 US claimed
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO claimed
US-9267214-B2 Aluminum recovery process BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-02-23 US disclosed
US-20110000782-A1 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2011-01-06 US disclosed
WO-2009131692-A1 SUBSTRATES FOR DELIVERY OF PHYSIOLOGICALLY ACTIVE AGENTS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2009-10-29 WO disclosed
WO-2009102419-A2 ALUMINUM RECOVERY PROCESS THE UNIVERSITY OF ALABAMA (US) 2009-08-20 WO disclosed