Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602400 | 0.83 | TDP1 (0.51) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9600761 | 0.83 | TDP1 (0.51) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10696879 | 0.83 | TDP1 (0.67) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9601597 | 0.81 | KMT2A (0.62) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9503150 | 0.80 | TDP1 (0.50) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9546892 | 0.80 | TDP1 (0.55) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9601648 | 0.80 | TDP1 (0.49) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL10452398 | 0.75 | LMNA (0.56) | TDP1KMT2AMEN1TTRPPOX | |
| SCHEMBL9503159 | 0.72 | TDP1 (0.38) | TDP1KMT2AMEN1ALDH1A1TBXA2R | |
| SCHEMBL10696902 | 0.72 | TDP1 (0.73) | TDP1KMT2AMEN1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357807-B1 | NOVEL 2-NITRO-5-(SUBSTITUTED PHENOXY) BENZOHYDROXIMIC ACID DERIVATIVES | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-01-27 | — | — | EP | disclosed |
| US-4931088-A | HERBICIDES | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-06-05 | — | — | US | disclosed |
| EP-0357807-A1 | Novel 2-nitro-5-(substituted phenoxy) benzohydroximic acid derivatives | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-03-14 | — | — | EP | disclosed |