Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | HTR1A | P08908 | 1/20 | 0.67 |
| ▸ | DRD4 | P21917 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9586993 | 0.90 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| SCHEMBL9587786 | 0.88 | DRD2 (0.70) | DRD2HTR1ADRD4 | |
| SCHEMBL10784526 | 0.87 | DRD2 (0.66) | DRD2HTR1ADRD4 | |
| SCHEMBL9588981 | 0.87 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL10782541 | 0.86 | DRD2 (0.67) | DRD2HTR1ADRD4 | |
| SCHEMBL10787758 | 0.85 | DRD2 (0.62) | DRD2HTR1ADRD4 | |
| SCHEMBL9586881 | 0.82 | DRD2 (0.70) | DRD2HTR1ADRD4 | |
| SCHEMBL10836726 | 0.82 | DRD2 (0.73) | DRD2HTR1ADRD4 | |
| SCHEMBL9587936 | 0.81 | DRD2 (0.61) | DRD2HTR1ADRD4 | |
| Hydrochloric Acid SCHEMBL10836083 | 0.81 | DRD2 (0.73) | DRD2HTR1ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309544-B1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-10 | — | — | EP | claimed |
| EP-0309544-A1 | PSYCHOTROPIC BICYCLIC IMIDES. | AMERICAN HOME PROD (US) | 1989-04-05 | — | — | EP | claimed |
| WO-1988007530-A1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-10-06 | — | — | WO | claimed |
| US-4748240-A | Psychotropic bicyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | claimed |
| EP-0309544-B1 | PSYCHOTROPIC BICYCLIC IMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-02-10 | — | — | EP | disclosed |
| US-4748240-A | Psychotropic bicyclic imides | AMERICAN HOME PRODUCTS CORPORATION (US) | 1988-05-31 | — | — | US | disclosed |