Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 8/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9211867 | 1.00 | CYP2C9 (0.38) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL9209412 | 0.93 | NAMPT (0.38) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL5605989 | 0.86 | MEN1 (0.53) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL6460660 | 0.86 | MEN1 (0.53) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL29484650 | 0.82 | CYP2C19 (0.49) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL676076 | 0.82 | CYP2C19 (0.49) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL676077 | 0.82 | CYP2C19 (0.49) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL9218782 | 0.81 | — | — | |
| SCHEMBL8750786 | 0.80 | MEN1 (0.34) | CYP2C9CYP2C19MEN1ALOX15KMT2A | |
| SCHEMBL8750746 | 0.80 | HDAC1 (0.35) | CYP2C9CYP2C19MEN1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5223508-A | Hypotensive agents, vasodilators | KIRIN BEER KABUSHIKI KAISHA (JP) | 1993-06-29 | — | — | US | disclosed |