Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.58 |
| ▸ | CHUK | O15111 | 2/20 | 0.58 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.54 |
| ▸ | ACP1 | P24666 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 4/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22145812 | 0.87 | IKBKB (0.56) | IKBKBCHUKTLR7TOP2A | |
| SCHEMBL9603045 | 0.80 | IKBKB (0.72) | IKBKBCHUK | |
| SCHEMBL9551426 | 0.78 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL13533460 | 0.75 | IKBKB (0.49) | IKBKBCHUKTLR7KDM4ELMNA | |
| SCHEMBL4982007 | 0.74 | IKBKB (0.80) | IKBKBCHUK | |
| SCHEMBL13533468 | 0.73 | IKBKB (0.47) | IKBKBCHUKTLR7KDM4ELMNA | |
| SCHEMBL8297242 | 0.73 | IKBKB (1.00) | IKBKBCHUK | |
| SCHEMBL13533472 | 0.73 | IKBKB (0.47) | IKBKBCHUKTLR7KDM4ELMNA | |
| SCHEMBL12733961 | 0.73 | ACP1 (0.54) | TLR7ACP1TOP2ACASP6NPSR1 | |
| SCHEMBL14537693 | 0.72 | IKBKB (0.48) | IKBKBCHUKTLR7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0310950-B1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| EP-0145340-B1 | 1H-Imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1990-01-24 | — | — | EP | disclosed |
| EP-0310950-A1 | Quinoline intermediates for the synthesis of 1H-imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amimes | RIKER LABORATORIES, INC. (US) | 1989-04-12 | — | — | EP | disclosed |
| US-4698348-A | 1H-imidazo[4,5-c]quinolines and their use as bronchodilating agents | RIKER LABORATORIES, INC. (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0145340-A2 | 1H-Imidazo[4,5-c]quinolines and 1H-imidazo[4,5-c]quinolin-4-amines | RIKER LABORATORIES, INC. (US) | 1985-06-19 | — | — | EP | disclosed |