Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601229 | 1.00 | TBXAS1 (0.69) | TBXAS1TBXA2R | |
| SCHEMBL9601444 | 0.88 | TBXA2R (0.76) | TBXAS1TBXA2R | |
| SCHEMBL9601449 | 0.88 | TBXA2R (0.76) | TBXAS1TBXA2R | |
| SCHEMBL9602647 | 0.85 | TBXA2R (0.81) | TBXAS1TBXA2R | |
| SCHEMBL9602658 | 0.85 | TBXA2R (0.81) | TBXAS1TBXA2R | |
| SCHEMBL9601865 | 0.84 | TBXAS1 (0.72) | TBXAS1TBXA2R | |
| SCHEMBL9601757 | 0.84 | TBXAS1 (0.72) | TBXAS1TBXA2R | |
| SCHEMBL9602582 | 0.83 | TBXA2R (0.85) | TBXAS1TBXA2R | |
| SCHEMBL9602592 | 0.83 | TBXA2R (0.85) | TBXAS1TBXA2R | |
| SCHEMBL7392867 | 0.82 | TBXAS1 (0.58) | TBXAS1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0221601-B1 | [[[(3-Pyridinyl)methylen]amino]oxy]alkanoic acids and esters | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-10 | — | — | EP | disclosed |
| US-5180832-A | Chemical intermediate for thromboxane A2 inhibitor | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-01-19 | — | — | US | disclosed |
| US-4963573-A | INHIBIT BIOSYNTHESIS OF THROMBOXANE A2 | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-10-16 | — | — | US | disclosed |
| US-4746671-A | THROMBOXANE SYNTHETASE INHIBITION | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-05-24 | — | — | US | disclosed |