Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.53 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.53 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.53 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601347 | 1.00 | ALDH1A1 (0.59) | ALDH1A1TSHRLMNACYP1A1CYP1B1 | |
| SCHEMBL16080090 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TSHRLMNACYP1A1CYP1B1 | |
| SCHEMBL11744336 | 0.85 | MAPT (0.69) | ALDH1A1TSHRLMNACYP1A1CYP1B1 | |
| SCHEMBL14648755 | 0.84 | TUBB1 (0.46) | ALDH1A1TSHRLMNACYP1A2TUBB4A | |
| SCHEMBL22050816 | 0.84 | TUBB1 (0.46) | ALDH1A1TSHRLMNACYP1A2TUBB4A | |
| SCHEMBL15986621 | 0.84 | CYP1A2 (0.49) | ALDH1A1TSHRLMNACYP1A1CYP1B1 | |
| SCHEMBL13521554 | 0.83 | MAPT (0.67) | ALDH1A1TSHRLMNACYP1A1CYP1B1 | |
| SCHEMBL16864095 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNACYP1A2MAPTPTGS2 | |
| SCHEMBL12045234 | 0.82 | ALDH1A1 (0.62) | ALDH1A1LMNACYP1A2MAPTPTGS2 | |
| SCHEMBL13128173 | 0.82 | ALDH1A1 (0.57) | ALDH1A1TSHRLMNACYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0227986-B1 | ISOINDOLINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4987235-A | Isoindoline derivatives and processes for their preparation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0227986-A1 | Isoindoline derivatives and processes for their preparation | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1987-07-08 | — | — | EP | disclosed |
| EP-0093610-A2 | Substituted urea herbicides | UNIROYAL, INC. (US) | 1983-11-09 | — | — | EP | disclosed |