Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.33 |
| ▸ | PGR | P06401 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602770 | 0.91 | NR1I2 (0.32) | NR1I2PGRTDP1L3MBTL1LMNA | |
| SCHEMBL9601930 | 0.91 | NR1I2 (0.33) | NR1I2PGRTDP1L3MBTL1LMNA | |
| SCHEMBL9602264 | 0.89 | NR1I2 (0.43) | CTDSP1NR1I2PGRTDP1L3MBTL1 | |
| SCHEMBL9600730 | 0.89 | NR1I2 (0.31) | NR1I2PGRTDP1L3MBTL1LMNA | |
| SCHEMBL9602520 | 0.87 | NR1I2 (0.43) | NR1I2PGRTDP1L3MBTL1MAPT | |
| SCHEMBL9601254 | 0.87 | NR1I2 (0.34) | NR1I2PGRTDP1MAPTPOLB | |
| SCHEMBL9600283 | 0.87 | NR1I2 (0.31) | NR1I2PGRTDP1L3MBTL1LMNA | |
| SCHEMBL9600364 | 0.87 | NR1I2 (0.31) | NR1I2PGRTDP1L3MBTL1LMNA | |
| SCHEMBL9600014 | 0.87 | TDP1 (0.34) | NR1I2PGRTDP1L3MBTL1MAPT | |
| SCHEMBL9600499 | 0.86 | NR1I2 (0.37) | NR1I2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |