Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 4/20 | 0.32 |
| ▸ | PGR | P06401 | 3/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.30 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.30 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9601608 | 0.91 | CTDSP1 (0.35) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9600730 | 0.90 | NR1I2 (0.31) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9601930 | 0.90 | NR1I2 (0.33) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9602264 | 0.88 | NR1I2 (0.43) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9600364 | 0.88 | NR1I2 (0.31) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9600283 | 0.88 | NR1I2 (0.31) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9602496 | 0.88 | NR1I2 (0.33) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9600669 | 0.87 | NR1I2 (0.42) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9600014 | 0.87 | TDP1 (0.34) | NR1I2PGRESR1PPARGTDP1 | |
| SCHEMBL9602584 | 0.86 | TDP1 (0.37) | NR1I2PGRESR1PPARGTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188254-B1 | CEPHEM COMPOUNDS, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-03-24 | — | — | EP | disclosed |
| US-4761410-A | MICROBIOCIDE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-02 | — | — | US | disclosed |
| EP-0188254-A2 | Cephem compounds, processes for preparation thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-23 | — | — | EP | disclosed |