Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 10/20 | 0.46 |
| ▸ | NPY1R | P25929 | 9/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL962751 | 0.85 | KCNH2 (0.42) | KCNH2NPY1R | |
| SCHEMBL963713 | 0.85 | KCNH2 (0.41) | KCNH2NPY1R | |
| SCHEMBL962739 | 0.84 | KCNH2 (0.45) | KCNH2NPY1R | |
| SCHEMBL964437 | 0.78 | KCNH2 (0.56) | KCNH2NPY1R | |
| SCHEMBL962684 | 0.76 | NPY1R (0.78) | KCNH2NPY1RSYK | |
| SCHEMBL965558 | 0.75 | KCNH2 (0.35) | KCNH2NPY1R | |
| SCHEMBL959741 | 0.74 | L3MBTL1 (0.35) | KCNH2NPY1R | |
| SCHEMBL3410009 | 0.71 | KCNH2 (0.50) | KCNH2NPY1RPIK3CB | |
| SCHEMBL960822 | 0.68 | KCNH2 (0.77) | KCNH2NPY1R | |
| SCHEMBL963131 | 0.65 | KCNH2 (0.42) | KCNH2NPY1RPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015181-A1 | ALKYLAMINOPYRIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015181-A1 | ALKYLAMINOPYRIDINE DERIVATIVE | NPY4R, NPY1R, NPY2R | KCNH2 1295/4885NPY1R 2/4885PIK3CB 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.