⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418051 | 1.00 | — | — | |
| SCHEMBL17356182 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL6186117 | 0.97 | CYP3A4 (0.56) | — | |
| Fluoride SCHEMBL27766501 | 0.97 | CYP3A4 (0.56) | — | |
| Iodide SCHEMBL31415635 | 0.97 | CYP3A4 (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL27721437 | 0.97 | CYP3A4 (0.56) | — | |
| Fluoromethane SCHEMBL28294738 | 0.95 | CYP3A4 (0.54) | — | |
| SCHEMBL27566690 | 0.89 | CYP3A4 (0.48) | — | |
| Piperazine SCHEMBL5550673 | 0.87 | CYP3A4 (0.46) | — | |
| SCHEMBL27536600 | 0.85 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4122 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115784987-B | Compound related to pneumonia as well as preparation method and application thereof and pharmaceutical composition | 国科温州研究院(温州生物材料与工程研究所) | 2025-05-27 | — | — | CN | claimed |
| CN-119912397-A | Gefitinib intermediate impurity YKYZ-C-GF-3, and preparation method and control method thereof | 江苏天士力帝益药业有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-116217437-B | Dacotinib intermediate, dacotinib and preparation method of Dacotinib | 沈阳药科大学 | 2025-02-11 | — | — | CN | claimed |
| CN-119390618-A | Method for preparing N- (3-chloro-4-fluorophenyl) -4-fluoro-3, 5-dimethylbenzenesulfonamide by one-pot method | 美益添生物医药(武汉)有限公司 | 2025-02-07 | — | — | CN | claimed |
| WO-2025000356-A1 | PALLADIUM-PLATED GOLD-BONDED COPPER WIRE AND ELECTROPLATING PROCESS THEREFOR | 上海万生合金材料有限公司 | 2025-01-02 | — | — | WO | claimed |
| CN-118930481-A | Preparation method of deuterated drug impurity norfloxacin-d 5 | 苏州默褔森新材料科技有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-115433135-B | Gefitinib method for purifying nylon | 山东鲁抗医药股份有限公司 | 2024-10-18 | — | — | CN | claimed |
| CN-113045504-B | Dacoti preparation method of nylon | 上海天慈国际药业有限公司 | 2024-09-17 | — | — | CN | claimed |
| CN-118561694-A | Method for continuously producing 3-chloro-4-fluoroaniline by adopting fixed bed reactor | 浙江德力装备有限公司 | 2024-08-30 | — | — | CN | claimed |
| CN-115925712-B | Targeted antitumor drug compound and preparation method and application thereof | 南京友怡医药科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-1038581-C | Process for preparing 3-(4-F-3-chlorophenamine)-2-ethoxycarbonyl ethyl acrylate | XU HONGCHANG (CN) | 1998-06-03 | — | — | CN | claimed |
| WO-1997016428-A1 | ISOQUINOLINE DERIVATIVES AND ISOQUINOLINE COMBINATORIAL LIBRARIES | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1997-05-09 | — | — | WO | claimed |
| CN-1026980-C | Synthesis process of alpha-ethoxyformyl-beta- (polyhalogenated anilino) -ethyl acrylate | NANJING PHARMACEUTIC INST (CN) | 1994-12-14 | — | — | CN | claimed |
| US-5354495-A | Homo- or copolymerizable through ethylenic unsaturation | NIPPON PAINT CO., LTD. (JP) | 1994-10-11 | — | — | US | claimed |
| EP-0177122-B1 | ACRYLAMIDE DERIVATIVES | Nippon Paint Co., Ltd. (JP) | 1992-04-01 | — | — | EP | claimed |
| CN-1057830-A | α-ethoxycarbonyl-β-(phenyl polyhalide amido)-ethyl propenoate synthesis technique | MEDICAL INST NANJING CITY (CN) | 1992-01-15 | — | — | CN | claimed |
| CN-1050375-A | The manufacture method of 3-(4-fluoro-3-chloroanilino)-2-ethoxycarbonyl ethyl acrylate | HU HONGCHANG (CN) | 1991-04-03 | — | — | CN | claimed |
| EP-0165375-B1 | DERIVATIVE OF PYRIDO-BENZOTHIAZINE WITH HIGH ANTI-MICROBIAL ACTIVITY | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1990-10-17 | — | — | EP | claimed |
| US-4668784-A | HALOANILINE WITH POTASSIUM THIOCYANATE | MEDIOLANUM FARMACEUTICI S.R.L. (IT) | 1987-05-26 | — | — | US | claimed |
| EP-0165375-A2 | Derivative of pyrido-benzothiazine with high anti-microbial activity | MEDIOLANUM FARMACEUTICI s.r.l. (IT) | 1985-12-27 | — | — | EP | claimed |