Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2243756 | 0.84 | SLC7A5 (0.51) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL2243752 | 0.84 | SLC7A5 (0.51) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL27456530 | 0.78 | SLC7A5 (0.62) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL28177422 | 0.78 | SLC7A5 (0.54) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL4453960 | 0.77 | SLC7A5 (0.67) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL27680265 | 0.77 | SLC7A5 (0.67) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL638519 | 0.76 | SLC7A5 (0.65) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL8012238 | 0.76 | SLC7A5 (0.65) | SLC7A5HDAC8TAAR1SLC6A2ESR1 | |
| SCHEMBL18025358 | 0.76 | SLC7A5 (0.65) | SLC7A5HDAC8DPP4TAAR1SLC6A2 | |
| SCHEMBL17738628 | 0.76 | SLC7A5 (0.65) | SLC7A5HDAC8DPP4TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5219996-A | RECOMBINANT ANTIBODIES AND METHODS FOR THEIR PRODUCTION IN WHICH SURFACE RESIDUES ARE ALTERED TO CYSTEINE RESIDUES FOR ATTACHMENT OF EFFECTOR OR RECEPTOR MOLECULES | CELLTECH LIMITED (GB) | 1993-06-15 | — | — | US | disclosed |
| EP-0348442-B1 | ALTERED ANTIBODY | CELLTECH LIMITED (GB) | 1993-01-27 | — | — | EP | disclosed |
| EP-0348442-A1 | ALTERED ANTIBODY | CELLTECH LIMITED (GB) | 1990-01-03 | — | — | EP | disclosed |
| WO-1989001782-A1 | RECOMBINANT ANTIBODY | CELLTECH LIMITED (GB) | 1989-03-09 | — | — | WO | disclosed |