SCHEMBL2243752

SCHEMBL2243752

NC(Cc1ccc(O)cc1)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.51
HDAC8 Q9BY41 3/20 0.47
DPP4 P27487 2/20 0.43
TAAR1 Q96RJ0 3/20 0.40
SLC6A2 P23975 1/20 0.40
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
TYR P14679 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2243756 1.00 SLC7A5 (0.51) SLC7A5HDAC8DPP4TAAR1SLC6A2
SCHEMBL8431258 0.87 PKM (0.51) SLC7A5HDAC8DPP4TYR
SCHEMBL27608702 0.87 PKM (0.51) SLC7A5HDAC8DPP4TYR
SCHEMBL5691529 0.87 PKM (0.51) SLC7A5HDAC8DPP4TYR
SCHEMBL9602009 0.84 SLC7A5 (0.53) SLC7A5HDAC8DPP4TAAR1SLC6A2
SCHEMBL31001590 0.82 LTA4H (0.54) DPP4
SCHEMBL8734045 0.81 KMT2A (0.46) ESR1ESR2
SCHEMBL21883998 0.81 KMT2A (0.46) ESR1ESR2
SCHEMBL29850264 0.80 DPP4 (0.50) DPP4
SCHEMBL29850100 0.80 DPP4 (0.50) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4092418-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS Life Technologies Corporation (US) 2022-11-23 EP disclosed
EP-3438131-B1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS LIFE TECHNOLOGIES CORP (US) 2022-03-16 EP disclosed
US-10676771-B2 Oligosaccharide modification and labeling of proteins Life Technologies Corporation (US) 2020-06-09 US disclosed
EP-3438131-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS Life Technologies Corporation (US) 2019-02-06 EP disclosed
EP-1987068-B1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS LIFE TECHNOLOGIES CORP (US) 2018-08-08 EP disclosed
US-20170166943-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS INVITROGEN CORPORATION 2017-06-15 US disclosed
US-20140377837-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS LIFE TECHNOLOGIES CORP (US) 2014-12-25 US disclosed
US-20140206848-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS Life Technologies Corporation (US) 2014-07-24 US disclosed
US-8785212-B2 Oligosaccharide modification and labeling of proteins Life Technologies Corporation (US) 2014-07-22 US disclosed
US-8716033-B2 Oligosaccharide modification and labeling of proteins Life Technologies Corporation (US) 2014-05-06 US disclosed
US-20110207171-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS Life Technologies Corporation (US) 2011-08-25 US disclosed
EP-1987068-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS INVITROGEN CORPORATION (US) 2008-11-05 EP disclosed
WO-2007095506-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS INVITROGEN CORPORATION (US) 2007-08-23 WO disclosed
US-20070190597-A1 OLIGOSACCHARIDE MODIFICATION AND LABELING OF PROTEINS INVITROGEN CORPORATION (US) 2007-08-16 US disclosed