Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.73 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.73 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.73 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.73 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.73 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.73 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.73 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.73 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.73 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.73 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ARG1 | P05089 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997125 | 1.00 | MEN1 (0.73) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL7806286 | 1.00 | MEN1 (0.73) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| SCHEMBL5058512 | 1.00 | MEN1 (0.73) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL120236 | 0.85 | MEN1 (1.00) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL13431267 | 0.85 | MEN1 (1.00) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL120235 | 0.85 | MEN1 (1.00) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL16392882 | 0.85 | MEN1 (1.00) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL120234 | 0.85 | MEN1 (1.00) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL20553546 | 0.85 | MEN1 (1.00) | MEN1KMT2AALDH1A1CYP1A2THRB | |
| Selfotel SCHEMBL9602901 | 0.83 | MEN1 (0.97) | MEN1KMT2AALDH1A1CYP1A2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217963-A | Antiischemic, antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5057506-A | Anticonvulsants, antispasmodic and antischemic agents | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| EP-0203891-B1 | CERTAIN PHOSPHONIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1991-05-15 | — | — | EP | disclosed |
| US-4906621-A | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4898854-A | NERVOUS SYSTEM DISORDERS | CIBA-GEIGY CORPORATION (US) | 1990-02-06 | — | — | US | disclosed |
| EP-0203891-A2 | Certain phosphonic acids and derivatives | CIBA-GEIGY AG (CH) | 1986-12-03 | — | — | EP | disclosed |