SCHEMBL960234

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL965293	0.89	MAP2K1 (0.71)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL29842959	0.89	MAP2K1 (0.71)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL962284	0.87	RAF1 (0.60)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL958918	0.85	MAP2K1 (0.54)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL23673983	0.83	MAP2K1 (0.51)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL29425486	0.83	MAP2K1 (0.51)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL31236923	0.83	MAP2K1 (0.51)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL958774	0.83	MAP2K1 (0.83)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL961069	0.82	MAP2K1 (0.82)	MAP2K1RAF1CYP2C9CYP3A4BRAF
	SCHEMBL959926	0.82	MAP2K1 (0.82)	MAP2K1RAF1CYP2C9CYP3A4BRAF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.