⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3101539 | 0.75 | — | — | |
| SCHEMBL18843152 | 0.72 | — | — | |
| SCHEMBL2105408 | 0.70 | L3MBTL1 (0.32) | — | |
| SCHEMBL2101962 | 0.70 | TDP1 (0.36) | — | |
| SCHEMBL2104586 | 0.70 | — | — | |
| SCHEMBL2106803 | 0.70 | — | — | |
| SCHEMBL21402220 | 0.70 | TSHR (0.31) | — | |
| SCHEMBL2105379 | 0.70 | L3MBTL1 (0.32) | — | |
| SCHEMBL73174 | 0.69 | — | — | |
| SCHEMBL16411207 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0123442-B1 | IMPROVEMENTS IN OR RELATING TO A PROCESS FOR PRODUCING BETA-LACTAM COMPOUNDS | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1988-06-15 | — | — | EP | disclosed |
| US-4675399-A | N-HYDROXY-2-AZETIDINONES; ACYLATION, SOLVOLYSIS | NOTRE DAME UNIVERSITY (US) | 1987-06-23 | — | — | US | disclosed |
| US-4565654-A | BETA-LACTAMASE ENZYME INHIBITORS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1986-01-21 | — | — | US | disclosed |
| EP-0123442-A1 | Improvements in or relating to a process for producing beta-lactam compounds | THE UNIVERSITY OF NOTRE DAME DU LAC (US) | 1984-10-31 | — | — | EP | disclosed |