Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810670 | 0.81 | GAA (0.49) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL8523619 | 0.81 | ALDH1A1 (0.64) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL28508900 | 0.79 | ALDH1A1 (0.67) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL12110047 | 0.79 | ALDH1A1 (0.67) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL12232725 | 0.78 | GAA (0.53) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL28738897 | 0.76 | GAA (0.56) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL7812310 | 0.76 | GAA (0.52) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL17726990 | 0.75 | ALDH1A1 (0.47) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL13240158 | 0.74 | GAA (0.59) | GAAL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL17727018 | 0.73 | ALDH1A1 (0.44) | GAAL3MBTL1ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |