Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24115655 | 0.76 | HKDC1 (0.32) | — | |
| SCHEMBL28524861 | 0.70 | — | — | |
| SCHEMBL24850398 | 0.69 | — | — | |
| SCHEMBL38102 | 0.68 | MAPT (0.39) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL14572406 | 0.67 | MAPT (0.42) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL7168251 | 0.67 | MAPT (0.37) | KDM4EALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL13892116 | 0.67 | MAPT (0.37) | KDM4EALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7168253 | 0.67 | MAPT (0.37) | KDM4EALDH1A1MAPTMAPK1TSHR | |
| SCHEMBL21318171 | 0.67 | GRM5 (0.33) | ALDH1A1 | |
| SCHEMBL19339183 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250676-B1 | NON-ENZYMATIC IMMUNOHISTOCHEMICAL STAINING SYSTEM AND REAGENTS | Immunomedics, Inc. (US) | 1993-03-10 | — | — | EP | disclosed |
| US-4792521-A | Non-enzymatic immunohistochemical staining system and reagents | IMMUNOMEDICS, INC. (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0250676-A2 | Non-enzymatic immunohistochemical staining system and reagents | Immunomedics, Inc. (US) | 1988-01-07 | — | — | EP | disclosed |