Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 8/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.42 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18293362 | 0.93 | KIF11 (0.50) | SERPINE1AURKATPX2KIF11SCN5A | |
| SCHEMBL306823 | 0.93 | KIF11 (0.50) | SERPINE1AURKATPX2KIF11SCN5A | |
| SCHEMBL168125 | 0.92 | KIF11 (0.47) | KIF11GRIN2B | |
| SCHEMBL27862141 | 0.92 | KIF11 (0.47) | KIF11GRIN2B | |
| SCHEMBL28910204 | 0.91 | SERPINE1 (0.49) | SERPINE1AURKATPX2KIF11SCN5A | |
| SCHEMBL4036809 | 0.90 | KIF11 (0.46) | KIF11GRIN2B | |
| SCHEMBL29087324 | 0.90 | KIF11 (0.46) | KIF11GRIN2B | |
| Fluoride SCHEMBL28371495 | 0.90 | KIF11 (0.46) | KIF11GRIN2B | |
| Water SCHEMBL27610464 | 0.90 | KIF11 (0.46) | KIF11GRIN2B | |
| Ammonia Solution, Strong SCHEMBL2163079 | 0.90 | KIF11 (0.46) | KIF11GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0334911-B1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK PATENT GmbH (DE) | 1993-02-10 | — | — | EP | claimed |