Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2388601 | 0.86 | TDP1 (0.52) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL2386760 | 0.86 | TDP1 (0.52) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1455140 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL9602952 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL18660176 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL18660185 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL1454054 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL22646172 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL18660180 | 0.81 | ALDH1A1 (0.66) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL11264853 | 0.81 | ALDH1A1 (0.47) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232623-B1 | 1-CARBACEPHALOSPORIN ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-4892942-A | 1-CARBA (DETHIA)CEPHALOSPORINS | ELI LILLY AND COMPANY (US) | 1990-01-09 | — | — | US | disclosed |
| US-4791106-A | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
| EP-0232623-A1 | 1-Carbacephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1987-08-19 | — | — | EP | disclosed |