Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9602272 | 0.84 | MEN1 (0.39) | FKBP1AALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL9602595 | 0.82 | FKBP1A (0.38) | FKBP1AALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9602206 | 0.81 | FKBP1A (0.32) | FKBP1AALDH1A1KMT2AMEN1IDH1 | |
| SCHEMBL9602485 | 0.74 | FKBP1A (0.40) | FKBP1AALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL468914 | 0.73 | FKBP1A (0.57) | FKBP1AALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL468912 | 0.73 | FKBP1A (0.57) | FKBP1AALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13373975 | 0.72 | FKBP1A (0.63) | FKBP1AALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL8438674 | 0.71 | FKBP1A (0.38) | FKBP1AALDH1A1MAPTKMT2ACYP3A4 | |
| SCHEMBL9198547 | 0.70 | GAA (0.56) | ALDH1A1MAPTHTTTSHRRECQL | |
| SCHEMBL16718840 | 0.70 | MEN1 (0.44) | ALDH1A1MAPTKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5217963-A | Antiischemic, antiepileptic agent | CIBA-GEIGY CORPORATION (US) | 1993-06-08 | — | — | US | disclosed |
| US-5057506-A | Anticonvulsants, antispasmodic and antischemic agents | CIBA-GEIGY CORPORATION (US) | 1991-10-15 | — | — | US | disclosed |
| US-4906621-A | Certain 2-carboxypiperidyl-alkylene phosphonic acids and esters thereof useful for the treatment of disorders responsive to N-methyl-D-aspartate receptor blockade | CIBA-GEIGY CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |