Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.56 |
| ▸ | STS | P08842 | 10/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10632191 | 0.86 | ESR1 (0.69) | ESR1ESR2STSNR3C1LMNA | |
| SCHEMBL10632112 | 0.86 | ESR1 (0.69) | ESR1ESR2STSNR3C1LMNA | |
| SCHEMBL9597951 | 0.84 | ESR1 (0.62) | ESR1ESR2STSNR3C1LMNA | |
| SCHEMBL27513595 | 0.82 | ESR1 (0.73) | ESR1ESR2STSNR3C1LMNA | |
| SCHEMBL10477574 | 0.82 | STS (0.70) | ESR1ESR2STSNR3C1PGR | |
| SCHEMBL8649397 | 0.82 | STS (0.70) | ESR1ESR2STSNR3C1PGR | |
| SCHEMBL10632020 | 0.82 | STS (0.70) | ESR1ESR2STSNR3C1PGR | |
| SCHEMBL10602167 | 0.82 | STS (0.70) | ESR1ESR2STSNR3C1PGR | |
| SCHEMBL10627659 | 0.82 | STS (0.70) | ESR1ESR2STSNR3C1PGR | |
| SCHEMBL8145253 | 0.82 | ESR1 (0.55) | ESR1ESR2STSNR3C1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4541957-A | Process for preparing iodovinyl-estradiol | THE GEORGE WASHINGTON UNIVERSITY (US) | 1985-09-17 | — | — | US | claimed |
| JP-5059092-A | — | — | None | — | — | JP | disclosed |
| JP-H0559092-A | INTERMEDIATE OF IODOVINYL-ESTRADIOL | UNIV GEORGE WASHINGTON | 1993-03-09 | — | — | JP | disclosed |
| US-4541957-A | Process for preparing iodovinyl-estradiol | THE GEORGE WASHINGTON UNIVERSITY (US) | 1985-09-17 | — | — | US | disclosed |