Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | PGR | P06401 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8145976 | 1.00 | ESR1 (0.55) | ESR1ESR2NR3C1LMNACYP2C19 | |
| SCHEMBL8151660 | 0.90 | ESR1 (0.52) | ESR1ESR2NR3C1LMNACYP2C19 | |
| SCHEMBL8159727 | 0.87 | STS (0.62) | ESR1NR3C1LMNACYP2C19PGR | |
| SCHEMBL8151691 | 0.86 | ESR1 (0.53) | ESR1ESR2NR3C1LMNACYP2C19 | |
| SCHEMBL8151131 | 0.86 | STS (0.66) | ESR1NR3C1LMNACYP2C19PGR | |
| SCHEMBL8153139 | 0.84 | ESR1 (0.72) | ESR1ESR2NR3C1LMNACYP2C19 | |
| SCHEMBL8153058 | 0.83 | STS (0.62) | ESR1NR3C1LMNACYP2C19PGR | |
| SCHEMBL8145946 | 0.83 | STS (0.64) | ESR1NR3C1LMNACYP2C19PGR | |
| SCHEMBL9603296 | 0.82 | ESR1 (0.56) | ESR1ESR2NR3C1LMNACYP2C19 | |
| SCHEMBL8151948 | 0.81 | STS (0.67) | ESR1NR3C1LMNACYP2C19PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | claimed |
| EP-0676202-B1 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | HOECHST MARION ROUSSEL INC (FR) | 2000-06-07 | — | — | EP | disclosed |
| EP-0676202-A2 | Use of aromatic steroids substituted in 3-position by a disubstituted aminoalkoxy chain for the manufacture of a medicament for the control of fertility, in particular male fertility | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | disclosed |