Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycolic Acid SCHEMBL9603329 | 0.86 | TAAR1 (0.44) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| SCHEMBL27016729 | 0.84 | TAAR1 (0.62) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| SCHEMBL77069 | 0.84 | TAAR1 (0.62) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| Sulfuric Acid SCHEMBL9603345 | 0.84 | TAAR1 (0.48) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| SCHEMBL167044 | 0.77 | CYP2C19 (0.64) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| SCHEMBL2295046 | 0.77 | CYP2C19 (0.64) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| SCHEMBL9588311 | 0.77 | TAAR1 (0.54) | TAAR1MAPTKMT2ACYP1A2CYP2D6 | |
| SCHEMBL2300536 | 0.77 | CYP2C19 (0.64) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| Sulfuric Acid SCHEMBL9603347 | 0.76 | TAAR1 (0.48) | CYP2C19HIF1ATAAR1MAPTKMT2A | |
| SCHEMBL1455824 | 0.76 | TAAR1 (0.50) | CYP2C19HIF1ATAAR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194644-A | Antitumor agents; treatment of leukemia | ASTA PHARMA AG (DE) | 1993-03-16 | — | — | US | claimed |