Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27016729 | 0.86 | TAAR1 (0.62) | TAAR1KIF11MAPTKMT2AKCNN4 | |
| SCHEMBL77069 | 0.86 | TAAR1 (0.62) | TAAR1KIF11MAPTKMT2AKCNN4 | |
| Sulfuric Acid SCHEMBL9603345 | 0.85 | TAAR1 (0.48) | TAAR1KIF11NR3C2CA2CA9 | |
| Glycolic Acid SCHEMBL9603329 | 0.81 | TAAR1 (0.44) | TAAR1KIF11MAPTKMT2ATACR1 | |
| SCHEMBL9588311 | 0.79 | TAAR1 (0.54) | TAAR1KIF11MAPTKMT2AKCNN4 | |
| Glycolic Acid SCHEMBL9603328 | 0.76 | CYP2C19 (0.47) | TAAR1KIF11MAPTKMT2AKCNN4 | |
| SCHEMBL27725243 | 0.72 | CYP1A2 (0.43) | TAAR1NR3C2CA2CA9CA1 | |
| SCHEMBL27746077 | 0.72 | CYP1A2 (0.43) | TAAR1NR3C2CA2CA9CA1 | |
| Tert-Butylbenzene SCHEMBL12477744 | 0.71 | ALDH1A1 (0.50) | NR3C2CA2CA9CA1CA5A | |
| SCHEMBL155932 | 0.71 | TAAR1 (0.52) | TAAR1MAPTKMT2AKCNN4TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5194644-A | Antitumor agents; treatment of leukemia | ASTA PHARMA AG (DE) | 1993-03-16 | — | — | US | claimed |