Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL712510 | 0.93 | NPC1 (0.43) | NPC1RAB9ALMNAPOLBTNKS | |
| SCHEMBL9323446 | 0.86 | NPC1 (0.38) | NPC1RAB9ALMNAPOLBTNKS | |
| SCHEMBL7698243 | 0.86 | TNKS (0.46) | NPC1RAB9ALMNAPOLBTNKS | |
| SCHEMBL8995885 | 0.85 | PTPN1 (0.33) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL28234016 | 0.84 | NPC1 (0.40) | NPC1RAB9ALMNAPOLBMEN1 | |
| SCHEMBL75918 | 0.83 | NPC1 (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL342550 | 0.81 | KDM4E (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL30112936 | 0.81 | KDM4E (0.46) | NPC1RAB9ALMNAPOLBALDH1A1 | |
| SCHEMBL2728270 | 0.81 | TNKS (0.50) | NPC1RAB9ALMNATNKSMEN1 | |
| SCHEMBL11035864 | 0.80 | NPC1 (0.36) | NPC1RAB9ALMNAPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5237071-A | Process for preparing 2,2'-methylene-bis(6-(2H-benzotriazol-2-yl)-4-hydrocarbyl phenols) | FAIRMOUNT CHEMICAL COMPANY, INC. (US) | 1993-08-17 | — | — | US | disclosed |