Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 4/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | PKM | P14618 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28019476 | 0.84 | THRA (0.37) | NPC1RAB9APOLBMAPTTDP1 | |
| SCHEMBL8809730 | 0.84 | NPC1 (0.50) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL712510 | 0.81 | NPC1 (0.43) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL9408839 | 0.80 | NPC1 (0.41) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL346033 | 0.80 | SETDB1 (0.40) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL9603768 | 0.80 | NPC1 (0.42) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL508931 | 0.78 | NPC1 (0.34) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL11408530 | 0.77 | NPC1 (0.34) | NPC1RAB9APOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL9408934 | 0.77 | NPC1 (0.47) | NPC1RAB9APOLBMEN1KMT2A | |
| SCHEMBL6530701 | 0.76 | PTPN1 (0.39) | NPC1RAB9APOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4576870-A | ACRYLIC POLYMER AS UV ABSORBER | ROHM GMBH (DE) | 1986-03-18 | — | — | US | disclosed |